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CHROMATIN AND EPIGENETIC REGULATION

Rothbart Laboratory
Our mission is to implement innovative scientific approaches and develop useful tools, reagents and therapeutics that advance our understanding of chromatin function in human health and disease. Central to the success of this mission is our dedication to the education and training of scientists to prepare them to become leaders in the scientific community.

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Featured News

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5 Dec. 2018 Teaming up to accelerate scientific discovery

20 Sept. 2017 $2.375 million federal award to study epigenetic control systems, inform drug discovery 

6 Aug. 2015 Meet the author: Scott Rothbart
Molecular Cell

FEATURED PUBLICATIONS

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Cornett EM et al. A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity. Sci Adv.

Shah RN et al. Examining the roles of H3K4 methylation states with systematically characterized antibodies. Mol Cell. 

Vaughan RM et al. Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1. Proc Natl Acad Sci U S A.

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