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CHROMATIN AND EPIGENETIC REGULATION
Our mission is to implement innovative scientific approaches and develop useful tools, reagents, and therapeutics that advance our understanding of chromatin function in key areas of biomedical research. Central to the success of this mission is our dedication to the education and training of scientists to prepare them to become leaders in society.
News
Making an early impact: Three questions for Dr. Rochelle Tiedemann
VAI Voice
3 November 2016 New computational tool may speed drug discovery
7 September 2016 The whole of epigenetic regulation may be more than the sum of its parts
Let’s get physical – adventures in the dry lab
VAI Voice
Meet the author: Scott Rothbart
Molecular Cell
23 July 2015 New antibody specificity portal bolsters biomedical research reliability
1 April 2015 Van Andel Research Institute’s center for epigenetics adds new assistant professor
FEATURED PUBLICATIONS
Harrison J et al. Hemi-methylated DNA regulates DN methylation inheritance through allosteric activation of H3 ubiquitylation for UHRF1. eLife.
Cornett EM et al. Substrate specificity profiling of histone-modifying enzymes by peptide microarray. Methods Enzymol
Dickson BM et al. ArrayNinja: An open source platform for unified planning and analysis of microarray experiments. Methods Enzymol
Rothbart SB et al. An interactive database for the assessment of histone specific antibody. Mol Cell
The Rothbart Lab participated in the annual VARI Scientific Retreat last week at beautiful Crystal Mountain. Highlights were keynotes from Karolin Luger and Joe Ecker. And big congrats to lab members Evan Cornett and Robert Vaughan for bringing home awards in this year’s poster contest!
A collaboration with our VARI colleagues Karsten Melcher and Eric Xu was published last week. Big congrats to everyone involved!
Research brief: What do TOPLESS plants and humans have in common? - VAI
vai.org
A protein that sometimes leads to topless plants may hold the key for better understanding how the genetic code is read and regulated in all living things.